Diagnostic Accuracy in Acute Venous Thromboembolism: Comparing D-Dimer, Thrombin Generation, Overall Hemostatic Potential, and Fibrin Monomers
نویسندگان
چکیده
منابع مشابه
Thrombin generation and venous thromboembolism.
Venous thromboembolism is a chronic and potential fatal disease. Determination of recurrence risk is time-consuming and costly, and sometimes not feasible: many patients carry more than one risk factor, the relevance of some factors with regard to risk of recurrence is unknown, and existence of thus far unknown risk factors must be considered. A laboratory assay that measures multifactorial thr...
متن کاملPrediction of recurrent venous thromboembolism by endogenous thrombin potential and D-dimer.
BACKGROUND Increased thrombin generation is associated with an increased risk of recurrent venous thromboembolism. We investigated the relation between endogenous thrombin potential (ETP) and risk of recurrent venous thromboembolism and evaluated whether prediction of recurrence can be improved by a combined analysis of ETP and D-dimer. METHODS We followed 861 patients with first spontaneous ...
متن کاملAssociations between venous thromboembolism onset, D-dimer, and soluble fibrin monomer complex after total knee arthroplasty
BACKGROUND Prevention and early detection of venous thromboembolism (VTE) is important after arthroplasty of the lower limb. The purpose of this study was to investigate the associations between VTE and hemostatic markers after minimally invasive total knee arthroplasty (MIS-TKA). METHODS We performed a retrospective study of 50 patients (55 knees) who underwent primary unilateral MIS-TKA wit...
متن کاملD-dimer testing in suspected venous thromboembolism: an update.
Fibrin is the main thrombus component. Its production being definitely lower in in-patients than in outpatients. is followed by activation of the fibrinolytic system, resulting in plasmin generation and subsequent fibrin lysis (Figure 1). Dissolution of crosslinked fibrin leads to formation of specific degradation products, includMethods for measuring DD in blood ing D-dimer (DD),1 which can be...
متن کاملD-dimer levels and risk of recurrent venous thromboembolism.
CONTEXT Widespread screening of patients with venous thromboembolism (VTE) for thrombophilic risk factors has become common clinical practice. Because of the increasing number of risk factors, assessing the risk of recurrence in an individual patient is intricate; therefore, a laboratory method that measures multifactorial thrombophilia is required. OBJECTIVE To prospectively study the relati...
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ژورنال
عنوان ژورنال: TH Open
سال: 2020
ISSN: 2512-9465
DOI: 10.1055/s-0040-1714210